NOMO1 and CASP4

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study)
HPRD (in vitro, in vivo)

		NOMO1	CASP4
Description		NODAL modulator 1	caspase 4
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Extracellular Region Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Protein-containing Complex IPAF Inflammasome Complex NLRP3 Inflammasome Complex AIM2 Inflammasome Complex
	Molecular Function	Molecular_function Protein Binding Carbohydrate Binding	Cysteine-type Endopeptidase Activity Protein Binding CARD Domain Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
	Biological Process	Biological_process Negative Regulation Of Nodal Signaling Pathway	Proteolysis Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Protein Autoprocessing Regulation Of Apoptotic Process Innate Immune Response Regulation Of Inflammatory Response Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Pyroptosis Intrinsic Apoptotic Signaling Pathway Execution Phase Of Apoptosis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Amyloid-beta
Pathways			NOD1/2 Signaling Pathway
Drugs		Theophylline	Incadronic acid
Diseases
GWAS			Major depressive disorder ( 29317602)
Interacting Genes		12 interacting genes: ATF7IP BAG6 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	16 interacting genes: APAF1 APP CASP10 CASP14 CASP3 CASP8 DSP ELF4 IL18 IL1B IL37 MYH9 NOD1 PLA2G4A PSEN1 SERPINB9
Entrez ID		23420	837
HPRD ID		11398	04047
Ensembl ID		ENSG00000103512	ENSG00000196954
Uniprot IDs		Q15155	P49662
PDB IDs			6KMZ 6NRY
Enriched GO Terms of Interacting Partners?
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