PHF24 and SIGMAR1

Data Source:
BioGRID (affinity chromatography technology)

		PHF24	SIGMAR1
Description		PHD finger protein 24	sigma non-opioid intracellular receptor 1
Image
GO Annotations	Cellular Component		Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Opioid Receptor Activity Protein Binding
	Biological Process	Gamma-aminobutyric Acid Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization
Pathways			Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		5 interacting genes: GNAI3 PFDN5 THBD TRIM35 ZNF552	3 interacting genes: ANK2 ITPR3 PDZD11
Entrez ID		23349	10280
HPRD ID		19412	03580
Ensembl ID		ENSG00000122733	ENSG00000147955
Uniprot IDs		Q9UPV7	A2A3U5 B4DR71 Q99720
PDB IDs		1WIL 5XHT	5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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