DIP2A and BACE2

Data Source:
BioGRID (affinity chromatography technology)

		DIP2A	BACE2
Description		disco interacting protein 2 homolog A	beta-secretase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cell Surface Membrane Dendritic Spine	Endosome Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane Dense Core Granule
	Molecular Function	Acetate-CoA Ligase Activity Protein Binding	Aspartic-type Endopeptidase Activity Protein Binding
	Biological Process	Acetyl-CoA Biosynthetic Process Negative Regulation Of Gene Expression Dendritic Spine Morphogenesis Positive Regulation Of Peptidyl-lysine Acetylation	Proteolysis Membrane Protein Ectodomain Proteolysis Peptide Hormone Processing Glucose Homeostasis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Astrocyte Activation Amyloid-beta Metabolic Process
Pathways
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Lymphocyte counts ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30224653) White blood cell count ( 32888494)	Adult body size ( 32376654) Body mass index ( 25673413) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Elevated fasting plasma glucose ( 30004843) Glycemic traits (pregnancy) ( 23903356)
Interacting Genes		19 interacting genes: ADAMTSL4 CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L IQUB JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43	3 interacting genes: APP GGA1 GGA2
Entrez ID		23181	25825
HPRD ID		07611	05744
Ensembl ID		ENSG00000160305	ENSG00000182240
Uniprot IDs		Q14689 Q96NX2	Q9Y5Z0
PDB IDs			2EWY 3ZKG 3ZKI 3ZKM 3ZKN 3ZKQ 3ZKS 3ZKX 3ZL7 3ZLQ 4BEL 4BFB 6JSZ 6UJ0 6UJ1
Enriched GO Terms of Interacting Partners?
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