LPIN1 and RRM2

Data Source:
BioGRID (two hybrid)

		LPIN1	RRM2
Description		lipin 1	ribonucleotide reductase regulatory subunit M2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane	Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding Phosphatidate Phosphatase Activity	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Metal Ion Binding
	Biological Process	Triglyceride Mobilization Phosphatidylethanolamine Biosynthetic Process Phosphatidylcholine Biosynthetic Process Mitotic Nuclear Envelope Disassembly Fatty Acid Catabolic Process Dephosphorylation Triglyceride Biosynthetic Process Animal Organ Regeneration Cellular Response To Insulin Stimulus Cellular Lipid Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cold-induced Thermogenesis	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Replication Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Negative Regulation Of G0 To G1 Transition
Pathways		Synthesis of PC Synthesis of PE Depolymerisation of the Nuclear Lamina Triglyceride biosynthesis	Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs			Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483) Post bronchodilator percent predicted FEV1 in smoking ( 30068317)	Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)
Interacting Genes		1 interacting genes: CDK6	9 interacting genes: CDH1 CDK1 DNM1L KAT5 PLK3 RRM1 RRM2B SDCBP TP53
Entrez ID		23175	6241
HPRD ID		09271	01587
Ensembl ID		ENSG00000134324	ENSG00000171848
Uniprot IDs		Q14693	P31350
PDB IDs			2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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