RRP1B and CLDN14

Data Source:
BioGRID (biochemical)

		RRP1B	CLDN14
Description		ribosomal RNA processing 1B	claudin 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Preribosome, Large Subunit Precursor Preribosome, Small Subunit Precursor	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	RRNA Processing MRNA Processing Apoptotic Process RNA Splicing Negative Regulation Of Phosphatase Activity Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of RNA Splicing Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases			Deafness, autosomal recessive
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Diastolic blood pressure ( 28135244 27618447) Mean corpuscular hemoglobin ( 27863252) Refractive error ( 32231278) Systolic blood pressure ( 27618447)	Blood urea nitrogen levels ( 31152163) Bone mineral density ( 24249740) Estimated glomerular filtration rate ( 31152163 31015462) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Kidney stones ( 26272126 19561606 31729369) Red blood cell count ( 32888494) Serum parathyroid hormone levels ( 27927781) Urate levels ( 31578528) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Urolithiasis ( 30975718)
Interacting Genes		4 interacting genes: CSNK2A1 LSM1 PPP1CC SRPK2	4 interacting genes: CTXN3 MAL PLEKHA1 PLLP
Entrez ID		23076	23562
HPRD ID		10009	05727
Ensembl ID		ENSG00000160208	ENSG00000159261
Uniprot IDs		Q14684	O95500
PDB IDs
Enriched GO Terms of Interacting Partners?
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