FOXJ1 and GATA6

Data Source:
BioGRID (two hybrid)

		FOXJ1	GATA6
Description		forkhead box J1	GATA binding protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nuclear Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Kinase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Actin Cytoskeleton Organization Ciliary Basal Body Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Cellular Protein Localization Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Activation Of GTPase Activity Positive Regulation Of Lung Ciliated Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Liver Development Sebaceous Gland Cell Differentiation Regulation Of Antimicrobial Humoral Response Outflow Tract Septum Morphogenesis Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Regulation Of Transcription By RNA Polymerase II Phospholipid Metabolic Process Endodermal Cell Fate Determination Blood Coagulation Male Gonad Development Cardiac Muscle Hypertrophy In Response To Stress Epithelial Cell Differentiation Response To Retinoic Acid Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Transforming Growth Factor Beta2 Production Tube Morphogenesis Response To Drug Negative Regulation Of Apoptotic Process Response To Estrogen Cellular Protein Metabolic Process Cell Fate Commitment Positive Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Formation Smooth Muscle Cell Differentiation Positive Regulation Of Cardioblast Differentiation Cardiac Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Proliferation Lung Saccule Development Club Cell Differentiation Type II Pneumocyte Differentiation Intestinal Epithelial Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Response To Growth Factor Positive Regulation Of Cell Cycle Arrest Cellular Response To Gonadotropin Stimulus Cellular Response To Hypoxia Cellular Response To BMP Stimulus Skin Epidermis Development Positive Regulation Of Cardiac Muscle Myoblast Proliferation Positive Regulation Of Transforming Growth Factor Beta Activation Negative Regulation Of Sebum Secreting Cell Proliferation
Pathways			Surfactant metabolism Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Diverticular disease ( 30177863) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) LDL cholesterol ( 25961943) Lung function (FEV1/FVC) ( 30804560) Resting heart rate ( 27798624) Severe progression in rheumatoid arthritis ( 29065906) Tuberculosis ( 20694014)
Interacting Genes		8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2	7 interacting genes: CRIP2 EP300 HHEX KLF2 KPNA3 MED1 NKX2-1
Entrez ID		2302	2627
HPRD ID		03798	09043
Ensembl ID		ENSG00000129654	ENSG00000141448
Uniprot IDs		A0A024R8P1 Q92949	Q92908
PDB IDs
Enriched GO Terms of Interacting Partners?
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