FOXJ1 and FBXO22

Data Source:
BioGRID (affinity chromatography technology)

		FOXJ1	FBXO22
Description		forkhead box J1	F-box protein 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Z Disc
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Actin Cytoskeleton Organization Ciliary Basal Body Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Cellular Protein Localization Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Activation Of GTPase Activity Positive Regulation Of Lung Ciliated Cell Differentiation	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Skeletal Muscle Fiber Development
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Creatinine levels ( 29403010) Urate levels in obese individuals ( 25811787)
Interacting Genes		8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2	1 interacting genes: SNAI1
Entrez ID		2302	26263
HPRD ID		03798	16437
Ensembl ID		ENSG00000129654	ENSG00000167196
Uniprot IDs		A0A024R8P1 Q92949	Q8NEZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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