FAAH and SLC2A1

Data Source:
BioGRID (affinity chromatography technology)

		FAAH	SLC2A1
Description		fatty acid amide hydrolase	solute carrier family 2 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytoskeleton Integral Component Of Membrane Organelle Membrane	Golgi Membrane Photoreceptor Inner Segment Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Intercalated Disc Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Sarcolemma Melanosome Extracellular Exosome Blood Microparticle Presynapse
	Molecular Function	Amidase Activity Protein Binding Fatty Acid Amide Hydrolase Activity Acylglycerol Lipase Activity Oleamide Hydrolase Activity Anandamide Amidohydrolase Activity	Long-chain Fatty Acid Transporter Activity Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity
	Biological Process	Fatty Acid Catabolic Process Arachidonic Acid Metabolic Process Monoacylglycerol Catabolic Process	Response To Hypoxia Lactose Biosynthetic Process Central Nervous System Development Female Pregnancy Regulation Of Glucose Transmembrane Transport Long-chain Fatty Acid Import Across Plasma Membrane L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Photoreceptor Cell Maintenance Regulation Of Insulin Secretion Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response Glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier Response To Thyroglobulin Triiodothyronine Glucose Transmembrane Transport
Pathways		Arachidonic acid metabolism	Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis
Drugs		Thiopental Methoxy arachidonyl fluorophosphonate 1-Dodecanol 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acid 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid Fostamatinib Medical Cannabis Nabiximols	Resveratrol Carboxymethylcellulose
Diseases			GLUT1 deficiency syndrome (GLUT1DS); Glucose transport defect of the blood-brain barrier Primary torsion dystonia (PTD)
GWAS		Body mass index ( 26426971) Lipid or lipoprotein levels ( 23696881)	Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pre-treatment viral load in HIV-1 infection ( 31219150) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: NOTCH2NLA	15 interacting genes: CALR CANX CCR2 COPS6 GAPDH GIPC1 GPR35 HSPB2 LTB4R2 PDIA3 PTK2B STOM SUMO1 UBE2I VHL
Entrez ID		2166	6513
HPRD ID		04244	00683
Ensembl ID		ENSG00000117480	ENSG00000117394
Uniprot IDs		O00519 Q9UG55	P11166 Q59GX2
PDB IDs			1SUK 4PYP 5EQG 5EQH 5EQI
Enriched GO Terms of Interacting Partners?
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