LVRN and SEMA6A

Data Source:
BioGRID (two hybrid)

		LVRN	SEMA6A
Description		laeverin	semaphorin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane	Extracellular Space Integral Component Of Plasma Membrane Integral Component Of Membrane Axon
	Molecular Function	Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Protein Binding Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	Proteolysis Signal Transduction Regulation Of Blood Pressure Peptide Catabolic Process	Neural Crest Cell Migration Apoptotic Process Cytoskeleton Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Animal Organ Morphogenesis Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Negative Regulation Of ERK1 And ERK2 Cascade Semaphorin-plexin Signaling Pathway Negative Regulation Of Cell Adhesion Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Neuron Migration
Pathways			Other semaphorin interactions
Drugs
Diseases
GWAS		Spontaneous preterm birth without premature rupture of membranes ( 31194736)	Allergic rhinitis ( 22036096) Amyotrophic lateral sclerosis ( 19451621) Blood protein levels ( 29875488) Body mass index ( 27296613) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cortical surface area (MOSTest) ( 32665545) Eosinophilic esophagitis ( 25017104) High chromosomal aberration frequency (chromatid type) ( 31586183) Periodontitis (DPAL) ( 24024966) Subcortical volume (MOSTest) ( 32665545) Wegener's granulomatosis ( 23740775)
Interacting Genes		2 interacting genes: IFIT3 LMNA	6 interacting genes: EVL ITSN2 SH3RF1 SORBS1 SORBS2 UBE2I
Entrez ID		206338	57556
HPRD ID		07118	06906
Ensembl ID		ENSG00000172901	ENSG00000092421
Uniprot IDs		Q0P5U8 Q6Q4G3	A0A0A0MQU6 Q9H2E6
PDB IDs			6WTS
Enriched GO Terms of Interacting Partners?
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