STT3B and DDR2

Data Source:
BioGRID (affinity chromatography technology)

		STT3B	DDR2
Description		STT3 oligosaccharyltransferase complex catalytic subunit B	discoidin domain receptor tyrosine kinase 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Actin Cytoskeleton Apical Plasma Membrane Receptor Complex
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding Collagen Binding ATP Binding Protein Tyrosine Kinase Collagen Receptor Activity
	Biological Process	Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Co-translational Protein Modification Post-translational Protein Modification	Ossification Endochondral Bone Growth Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Fibroblast Migration Peptidyl-tyrosine Phosphorylation Extracellular Matrix Organization Collagen Fibril Organization Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of Kinase Activity Regulation Of Tissue Remodeling Chondrocyte Proliferation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Protein Kinase Activity Protein Autophosphorylation Positive Regulation Of Fibroblast Proliferation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Extracellular Matrix Disassembly
Pathways			Non-integrin membrane-ECM interactions
Drugs			Regorafenib Fostamatinib
Diseases			Spondylometaepiphyseal dysplasia, short limb-hand type; Spondylometaepiphyseal dysplasia, short limb-abnormal calcification type
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Dupuytren's disease ( 28886342) Height ( 31562340)
Interacting Genes		1 interacting genes: INCA1	4 interacting genes: COL1A1 COL3A1 SHC1 SRC
Entrez ID		201595	4921
HPRD ID		12268	01868
Ensembl ID		ENSG00000163527	ENSG00000162733
Uniprot IDs		Q8TCJ2	A0A024R906 Q16832
PDB IDs		6S7T	2WUH 2Z4F 6FER
Enriched GO Terms of Interacting Partners?
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