STT3B and CYP51A1

Data Source:
BioGRID (proximity labelling technology)

		STT3B	CYP51A1
Description		STT3 oligosaccharyltransferase complex catalytic subunit B	cytochrome P450 family 51 subfamily A member 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding	Monooxygenase Activity Iron Ion Binding Sterol 14-demethylase Activity Oxidoreductase Activity Heme Binding
	Biological Process	Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Co-translational Protein Modification Post-translational Protein Modification	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Protein Secretion Demethylation Negative Regulation Of Amyloid-beta Clearance
Pathways			Cholesterol biosynthesis Endogenous sterols Activation of gene expression by SREBF (SREBP) EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs			Tioconazole Itraconazole Levoketoconazole (S)-econazole
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lifespan ( 25918517) Pulse pressure ( 30578418)
Interacting Genes		1 interacting genes: INCA1	1 interacting genes: ZNF420
Entrez ID		201595	1595
HPRD ID		12268	03381
Ensembl ID		ENSG00000163527	ENSG00000001630
Uniprot IDs		Q8TCJ2	A0A0C4DFL7 Q16850
PDB IDs		6S7T	3JUS 3JUV 3LD6 4UHI 4UHL 6Q2T 6UEZ
Enriched GO Terms of Interacting Partners?
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