DOCK2 and GNAL

Data Source:
BioGRID (affinity chromatography technology)

		DOCK2	GNAL
Description		dedicator of cytokinesis 2	G protein subunit alpha L
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Cytoskeleton Membrane Specific Granule Lumen Extracellular Exosome	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding T Cell Receptor Binding	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Membrane Raft Polarization Establishment Of T Cell Polarity Immunological Synapse Formation Myeloid Dendritic Cell Activation Involved In Immune Response Chemotaxis Small GTPase Mediated Signal Transduction Actin Cytoskeleton Organization Neutrophil Degranulation Positive Regulation Of GTPase Activity Macropinocytosis Positive Thymic T Cell Selection Negative Thymic T Cell Selection Alpha-beta T Cell Proliferation Regulation Of Defense Response To Virus By Virus Positive Regulation Of Phagocytosis	Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Chemical Stimulus
Pathways		Nef and signal transduction Neutrophil degranulation Factors involved in megakaryocyte development and platelet production	Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Body mass index and waist-hip ratio (pleiotropy) ( 29868124) Placental abruption ( 29884306) Pneumococcal bacteremia ( 27236921) Prostate cancer ( 29892016) Protein quantitative trait loci ( 18464913)	Age at first sexual intercourse ( 27089180) Alcohol dependence ( 26365420) Metabolite levels ( 23823483) QT interval (drug interaction) ( 23459443) Sensation seeking ( 30718321) Tandem gait ( 26219847) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		48 interacting genes: CALCOCO2 CARD10 CCNDBP1 CD247 CRKL CYSRT1 ELMO1 GOLGA6L9 HNRNPK HOXA1 KHDRBS1 KHDRBS2 KHDRBS3 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 MDFI MTDH MTUS2 NBPF19 NOTCH2NLA PAK2 PCSK5 PLEKHF2 PLSCR1 RAC1 RAC2 TENM4 TGM1 TRIM23 VAV1
Entrez ID		1794	2774
HPRD ID		09121	00758
Ensembl ID		ENSG00000134516	ENSG00000141404
Uniprot IDs		Q5XG91 Q92608	A8K1Y9 P38405
PDB IDs		2RQR 2YIN 3A98 3B13 6TGB 6TGC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?