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ASXL1 and DEFB116
Data Source:
BioGRID
(affinity chromatography technology)
ASXL1
DEFB116
Description
ASXL transcriptional regulator 1
defensin beta 116
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
PR-DUB Complex
Extracellular Region
Molecular Function
DNA Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Retinoic Acid Receptor Binding
Peroxisome Proliferator Activated Receptor Binding
Metal Ion Binding
Biological Process
Cell Morphogenesis
Heart Morphogenesis
Transcription, DNA-templated
Animal Organ Morphogenesis
Negative Regulation Of Lipid Storage
Protein Deubiquitination
Hemopoiesis
Response To Retinoic Acid
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Monoubiquitinated Histone H2A Deubiquitination
Regulation Of Kidney Size
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Thymus Development
Bone Marrow Development
Homeostasis Of Number Of Cells
Lung Saccule Development
Glomerular Visceral Epithelial Cell Development
Defense Response To Bacterium
Innate Immune Response
Pathways
UCH proteinases
Beta defensins
Defensins
Drugs
Diseases
C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
GWAS
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Inflammatory bowel disease (
28067908
)
Red cell distribution width (
32888494
)
Prudent dietary pattern (
28644415
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
6 interacting genes:
APP
GOLGA6L9
H1-2
SRPK1
STAT3
UBC
Entrez ID
171023
245930
HPRD ID
16516
19020
Ensembl ID
ENSG00000171456
ENSG00000215545
Uniprot IDs
Q498B9
Q8IXJ9
Q30KQ4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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