ZDHHC15 and TBXA2R

Data Source:
BioGRID (two hybrid)

		ZDHHC15	TBXA2R
Description		zinc finger DHHC-type palmitoyltransferase 15	thromboxane A2 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Integral Component Of Golgi Membrane Postsynapse	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Protein Targeting To Membrane Synaptic Vesicle Maturation Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Drug Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Pathways			Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor
Drugs			Ridogrel Seratrodast Morniflumate
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Interacting Genes		48 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4	35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15
Entrez ID		158866	6915
HPRD ID		06758	01768
Ensembl ID		ENSG00000102383	ENSG00000006638
Uniprot IDs		B3KY34 Q96MV8	P21731 Q05C92 Q0VAB0
PDB IDs			1LBN
Enriched GO Terms of Interacting Partners?
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