JAKMIP1 and CLNK

Data Source:
BioGRID (affinity chromatography technology)

		JAKMIP1	CLNK
Description		janus kinase and microtubule interacting protein 1	cytokine dependent hematopoietic cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Cytoskeleton Extrinsic Component Of Membrane Ribonucleoprotein Complex	Cytoplasm Protein-containing Complex Mast Cell Granule
	Molecular Function	RNA Binding Protein Binding Microtubule Binding Kinase Binding GABA Receptor Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Transport Cognition	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation
Pathways
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241) Response to angiotensin II receptor blocker therapy ( 22566498) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		19 interacting genes: BLK C18orf25 CBX8 CHRM3 DDX6 ENKD1 GABBR1 IL16 JAK1 MCRS1 MRPL11 PSMB1 SCNM1 TSGA10IP TYK2 USP2 YES1 YWHAG ZNHIT2	29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		152789	116449
HPRD ID		11292	14720
Ensembl ID		ENSG00000152969	ENSG00000109684
Uniprot IDs		B3KWB6 Q96N16	Q7Z7G1
PDB IDs
Enriched GO Terms of Interacting Partners?
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