CPN1 and STC2

Data Source:
BioGRID (affinity chromatography technology)

		CPN1	STC2
Description		carboxypeptidase N subunit 1	stanniocalcin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Peptide Metabolic Process Bradykinin Catabolic Process Protein Processing Regulation Of Complement Activation Response To Glucocorticoid	Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Gene Expression Response To Vitamin D Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia
Pathways		Regulation of Complement cascade	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Zinc ORE-1001 Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 29875488 28240269 23696881) Creatine kinase levels ( 29403010) Dermatomyositis ( 27153935) Femoral neck bone mineral density ( 22504420) General cognitive ability ( 29844566) Heel bone mineral density ( 30598549) Height ( 20881960) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757) Mean reticulocyte volume ( 32888494)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		6 interacting genes: C3 C5 CDC42 CLEC4G CPN2 KNG1	11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		1369	8614
HPRD ID		09120	04717
Ensembl ID		ENSG00000120054	ENSG00000113739
Uniprot IDs		P15169	O76061 Q6FHC9
PDB IDs		2NSM
Enriched GO Terms of Interacting Partners?
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