CKB and DIO3

Data Source:
BioGRID (genetic interference)

		CKB	DIO3
Description		creatine kinase B	iodothyronine deiodinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Dendrite Neuronal Cell Body Extracellular Exosome	Plasma Membrane Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding	Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity
	Biological Process	Creatine Metabolic Process Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process	Thyroid Hormone Generation Positive Regulation Of Multicellular Organism Growth Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Negative Regulation Of Eye Photoreceptor Cell Development Retinal Cone Cell Development Retinal Cone Cell Apoptotic Process
Pathways		Creatine metabolism	Regulation of thyroid hormone activity
Drugs		Creatine Phosphocreatine	Iopodic acid
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Metabolite levels ( 23823483) Pulse pressure ( 30224653) Type 1 diabetes ( 19966805)
Interacting Genes		15 interacting genes: ACD ARIH2 ASB9 CKM ERBB2 GOLGA2 ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63	3 interacting genes: APP PRMT5 PRMT7
Entrez ID		1152	1735
HPRD ID		00423	11867
Ensembl ID		ENSG00000166165	ENSG00000197406
Uniprot IDs		G3V4N7 P12277 V9HWH2	P55073 Q86TU3
PDB IDs		3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
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