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TMEM106A and TMEM86B
Data Source:
BioGRID
(two hybrid)
TMEM106A
TMEM86B
Description
transmembrane protein 106A
transmembrane protein 86B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Cytoplasm
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Molecular_function
Protein Binding
Protein Binding
Ether Hydrolase Activity
Identical Protein Binding
Alkenylglycerophosphocholine Hydrolase Activity
Alkenylglycerophosphoethanolamine Hydrolase Activity
Biological Process
Biological_process
Interleukin-1 Beta Production
Interleukin-6 Production
Tumor Necrosis Factor Production
CD80 Biosynthetic Process
CD86 Biosynthetic Process
Macrophage Activation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of MAPK Cascade
Innate Immune Response
Positive Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of Nitric Oxide Metabolic Process
Phosphatidylcholine Acyl-chain Remodeling
Ether Lipid Metabolic Process
Pathways
Acyl chain remodelling of PC
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Mean reticulocyte volume (
32888494
)
Phosphatidylethanolamine-ether levels (
31551469
)
Systemic lupus erythematosus (
33536424
28714469
)
Interacting Genes
13 interacting genes:
ARF1
ENTPD3
ERG28
GJB2
GOSR2
IGFBP5
RHOU
TMEM106C
TMEM107
TMEM128
TMEM86B
TNMD
TSPAN4
105 interacting genes:
AQP6
ARL13B
ARL6IP6
ASGR2
BCL2L13
BIK
BMP10
C2CD2L
CCDC167
CCDC34
CCL4
CD53
CD79A
CLRN1
CYB5B
DHRSX
DNAJC30
EBP
ERGIC3
ERP29
EVI2B
F11R
FAM209A
FAXDC2
FKBP7
FXYD6
GJA1
GJA4
GJA8
GOLM1
GPR37L1
GPX8
GUCA2A
HIBADH
HSD17B13
IER3IP1
IFITM3
KIR2DL3
LAPTM4B
LIME1
LSS
LY6D
MARCHF2
MFF
MGST3
MMGT1
MS4A14
MSMO1
MUC1
NDUFAF1
NEMP1
NINJ2
ORMDL2
OTULINL
PEX11G
PGRMC2
PIGF
PLN
PSCA
PTPN1
PTPN9
RHBDD1
RHOT2
RPRM
RTP2
SEC22B
SERINC2
SFRP1
SFT2D1
SFXN5
SLC10A6
SLC29A2
SLC35G2
SLC39A9
SMIM1
SNORC
SSMEM1
STOM
STX12
STX6
STX8
TEX29
THAP4
THBD
TIMM23
TMEM106A
TMEM107
TMEM120A
TMEM14A
TMEM14C
TMEM203
TMEM237
TMEM248
TMEM52B
TMEM60
TMPRSS2
TMX2
TREX1
TSNARE1
USE1
VAMP2
VAMP3
VAMP5
VAPA
ZDHHC22
Entrez ID
113277
255043
HPRD ID
11315
14540
Ensembl ID
ENSG00000184988
ENSG00000180089
Uniprot IDs
B7Z779
Q96A25
Q8N661
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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