MGAT4B and SLIT3

Data Source:
BioGRID (genetic interference)

		MGAT4B	SLIT3
Description		alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B	slit guidance ligand 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Stack Integral Component Of Membrane	Extracellular Space Mitochondrion
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding	Calcium Ion Binding Heparin Binding Roundabout Binding
	Biological Process	Protein N-linked Glycosylation N-glycan Processing Protein Phosphopantetheinylation	Aortic Valve Morphogenesis Atrioventricular Valve Morphogenesis Axon Guidance Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Cell Growth Cellular Response To Hormone Stimulus Roundabout Signaling Pathway Axon Extension Involved In Axon Guidance Negative Chemotaxis Response To Cortisol Ventricular Septum Morphogenesis Apoptotic Process Involved In Luteolysis Negative Regulation Of Chemokine-mediated Signaling Pathway
Pathways		Maturation of spike protein N-Glycan antennae elongation	Netrin-1 signaling Signaling by ROBO receptors Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Major depressive disorder ( 27479909) Plateletcrit ( 32888494)	Atrial fibrillation ( 30061737) Body mass index ( 31217584) Circulating leptin levels in high cardiovascular risk ( 31766143) Circulating leptin levels x sex interaction in high cardiovascular risk ( 31766143) Diastolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Gut microbiota (functional units) ( 27694959) Hallux valgus ( 32131869) Height ( 28552196 20881960 25282103 25429064 31562340) Inflammatory skin disease ( 25574825) Menarche (age at onset) ( 25231870) Non-word reading ( 30741946) Treatment resistant depression ( 30468137)
Interacting Genes		2 interacting genes: APPBP2 LRSAM1	2 interacting genes: CAPN1 ROBO2
Entrez ID		11282	6586
HPRD ID		05190	04775
Ensembl ID		ENSG00000161013	ENSG00000184347
Uniprot IDs		Q9UQ53	O75094
PDB IDs
Enriched GO Terms of Interacting Partners?
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