CHML and SERPINC1

Data Source:
HPRD (in vitro)

		CHML	SERPINC1
Description		CHM like Rab escort protein	serpin family C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	GDP-dissociation Inhibitor Activity GTPase Activator Activity Small GTPase Binding	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Protein Geranylgeranylation Positive Regulation Of GTPase Activity Post-translational Protein Modification	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Blood Coagulation, Intrinsic Pathway
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases			Inherited thrombophilia
GWAS		Daytime sleep phenotypes ( 27126917)	Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)
Interacting Genes		5 interacting genes: RAB1A RAB3A RAB5A RAB6A RABGGTB	6 interacting genes: F2 KLK1 KLK2 KLK6 PLG SDC2
Entrez ID		1122	462
HPRD ID		00341	00122
Ensembl ID		ENSG00000203668	ENSG00000117601
Uniprot IDs		P26374	A0A024R944 P01008
PDB IDs			1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
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