ATF7 and TAOK3

Data Source:
BioGRID (pull down)

		ATF7	TAOK3
Description		activating transcription factor 7	TAO kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Periphery	Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enzyme Binding CAMP Response Element Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding Sequence-specific Double-stranded DNA Binding	Protein Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Transferase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process	MAPK Cascade DNA Repair Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis
Pathways
Drugs		Pseudoephedrine	Fostamatinib
Diseases
GWAS		Basophil count ( 32888494) Electroencephalogram traits ( 25387704) Heel bone mineral density ( 30598549) Height ( 21998595 25429064 31562340 20189936) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Glucose homeostasis traits ( 25524916) Hip circumference ( 28552196) Loneliness ( 31518406) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Post bronchodilator FEV1 in COPD ( 26634245) Red cell distribution width ( 32888494 27863252) Systemic lupus erythematosus ( 19838195)
Interacting Genes		17 interacting genes: ATF2 FAM9B FCER2 FOS KASH5 MAPK9 MBD3 MITD1 OCIAD1 PTP4A1 PTP4A2 TAF12 TAF4 TAOK3 TMEM239 URI1 YY1	5 interacting genes: ATF7 ERN1 LRRK2 SMURF1 TRAF2
Entrez ID		11016	51347
HPRD ID		06968	11620
Ensembl ID		ENSG00000170653	ENSG00000135090
Uniprot IDs		P17544	G3V1Q8 Q9H2K8
PDB IDs			6BDN
Enriched GO Terms of Interacting Partners?
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