RAB10 and EFR3B

Data Source:
BioGRID (affinity chromatography technology)

		RAB10	EFR3B
Description		RAB10, member RAS oncogene family	EFR3 homolog B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network	Cytosol Plasma Membrane Actin Cytoskeleton
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding
	Biological Process	Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index in non-asthmatics ( 23517042) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 28552196) Inflammatory bowel disease ( 28067908) Type 1 diabetes ( 21980299)
Interacting Genes		9 interacting genes: APP ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		10890	22979
HPRD ID		06692	13824
Ensembl ID		ENSG00000084733	ENSG00000084710
Uniprot IDs		P61026	B3KT90 E7ESK9 Q9Y2G0
PDB IDs		5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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