PDPN and CELA2B

Data Source:
BioGRID (affinity chromatography technology)

		PDPN	CELA2B
Description		podoplanin	chymotrypsin like elastase 2B
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Cell Junction Filopodium Lamellipodium Membrane Cytoplasmic Vesicle Filopodium Membrane Microvillus Membrane Ruffle Membrane Cell Projection Membrane Raft Leading Edge Of Lamellipodium Tetraspanin-enriched Microdomain	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Water Transmembrane Transporter Activity Protein Binding Folic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Water Channel Activity Chemokine Binding Chaperone Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Cell Morphogenesis Lymphangiogenesis Amino Acid Transmembrane Transport Water Transport Amino Acid Transport Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Folic Acid Transport Platelet Activation Lung Development Positive Regulation Of Cell Migration Tube Morphogenesis Negative Regulation Of Apoptotic Process Wound Healing, Spreading Of Cells Lymph Node Development Positive Regulation Of Cellular Component Movement Response To Hyperoxia Lymphatic Endothelial Cell Fate Commitment Actin-mediated Cell Contraction Positive Regulation Of Extracellular Matrix Disassembly Cell-cell Adhesion Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Regulation Of Myofibroblast Contraction Regulation Of Lamellipodium Morphogenesis	Proteolysis
Pathways		GPVI-mediated activation cascade
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 29273807) Body size at age 10 ( 32376654) Estimated glomerular filtration rate ( 31015462) Hemoglobin ( 32888494) Resistant hypertension ( 30237584)
Interacting Genes		2 interacting genes: TMEM14B TOM1L1	4 interacting genes: CALCOCO2 KRT40 KRTAP3-1 ZDHHC15
Entrez ID		10630	51032
HPRD ID		16398	06496
Ensembl ID		ENSG00000162493	ENSG00000215704
Uniprot IDs		Q86YL7	P08218 Q6ISP9
PDB IDs		3WSR 4YO0 5XCV 7C94
Enriched GO Terms of Interacting Partners?
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