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PITRM1 and S100A7
Data Source:
BioGRID
(affinity chromatography technology)
PITRM1
S100A7
Description
pitrilysin metallopeptidase 1
S100 calcium binding protein A7
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Matrix
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Focal Adhesion
Azurophil Granule Lumen
Collagen-containing Extracellular Matrix
Molecular Function
Metalloendopeptidase Activity
Enzyme Activator Activity
Metallopeptidase Activity
Zinc Ion Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
Calcium-dependent Protein Binding
RAGE Receptor Binding
Biological Process
Proteolysis
Protein Targeting To Mitochondrion
Protein Processing
Regulation Of Catalytic Activity
Response To Reactive Oxygen Species
Angiogenesis
Epidermis Development
Positive Regulation Of T Cell Chemotaxis
Antimicrobial Humoral Response
Keratinocyte Differentiation
Response To Lipopolysaccharide
Neutrophil Degranulation
Innate Immune Response
Defense Response To Gram-negative Bacterium
Sequestering Of Metal Ion
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Granulocyte Chemotaxis
Positive Regulation Of Monocyte Chemotaxis
Pathways
Mitochondrial protein import
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Drugs
Ibuprofen
Zinc
8-anilinonaphthalene-1-sulfonic acid
Dexibuprofen
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Metabolite levels (
23823483
)
Scalp hair shape (
26926045
)
Blood protein levels (
30072576
)
Interacting Genes
8 interacting genes:
CLVS2
COPS5
EGFR
FABP5
RANBP9
S100A7L2
TGM2
UCHL5
Entrez ID
10531
6278
HPRD ID
07142
02645
Ensembl ID
ENSG00000107959
ENSG00000143556
Uniprot IDs
Q5JRX3
P31151
PDB IDs
4L3T
4NGE
4RPU
1PSR
2PSR
2WND
2WOR
2WOS
3PSR
4AQJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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