NXF1 and U2AF1

Data Source:
HPRD (in vitro, two hybrid)

		NXF1	U2AF1
Description		nuclear RNA export factor 1	U2 small nuclear RNA auxiliary factor 1
Image
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear Inclusion Body	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		108 interacting genes: ALYREF AUNIP BACH2 BECN1 BIN3 BIRC2 BLMH BTBD18 C10orf55 C12orf40 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CLK2 CLK3 CSNK2A1 DHX9 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF7 STRAP SYCP3 TBC1D14 TCP10L TEX9 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VPS28 XIST ZBED2 ZNF250 ZNF343 ZNF438	51 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		10482	7307
HPRD ID		04035	01871
Ensembl ID		ENSG00000162231	ENSG00000160201
Uniprot IDs		Q59E96 Q9UBU9	P0DN76 Q01081 Q7Z780
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U	1JMT
Enriched GO Terms of Interacting Partners?
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