TRDN and HRC

Data Source:
HPRD (in vitro, in vivo)

		TRDN	HRC
Description		triadin	histidine rich calcium binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen	Endoplasmic Reticulum Lumen Z Disc Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen
	Molecular Function	Signaling Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Ion Channel Binding	Calcium Ion Binding Protein Binding Ion Channel Binding ATPase Binding
	Biological Process	Cellular Calcium Ion Homeostasis Muscle Contraction Response To Bacterium Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction	Regulation Of Heart Rate Muscle Contraction Positive Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Peptidyl-serine Phosphorylation Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Heart Contraction Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Relaxation Of Cardiac Muscle Regulation Of Calcium Ion Transmembrane Transport
Pathways		Stimuli-sensing channels Ion homeostasis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Borderline personality disorder ( 28632202) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		10 interacting genes: ASPH CALM1 CASQ1 CASQ2 HRC KCNE4 PPIB PTPRN RYR1 SOCS3	2 interacting genes: TRDN ZNF699
Entrez ID		10345	3270
HPRD ID		04474	00818
Ensembl ID		ENSG00000186439	ENSG00000130528
Uniprot IDs		A0A590UJV0 H9ME53 Q13061 Q8IVK2	P23327
PDB IDs
Enriched GO Terms of Interacting Partners?
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