RGS19 and OSTM1

Data Source:
HPRD (two hybrid, in vitro)

		RGS19	OSTM1
Description		regulator of G protein signaling 19	osteoclastogenesis associated transmembrane protein 1
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GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle Membrane Raft	Lysosomal Membrane Cytosol Integral Component Of Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity Protein Binding
	Biological Process	Autophagy G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Negative Regulation Of Signal Transduction Response To Ethanol	Osteoclast Differentiation Ion Transmembrane Transport
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	Stimuli-sensing channels
Drugs
Diseases			Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic kidney disease ( 31152163) Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31152163) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Systolic blood pressure ( 30578418)	Major depressive disorder ( 29187746)
Interacting Genes		25 interacting genes: ALPP CATSPER1 CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 KRTAP5-6 LCE4A MAPK1 MAPK6 NUFIP2 OPRL1 OSTM1 OTX1 POU4F2 PRKCA PSMA1 TGFBR1 VASN	6 interacting genes: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20
Entrez ID		10287	28962
HPRD ID		05461	09628
Ensembl ID		ENSG00000171700	ENSG00000081087
Uniprot IDs		B4DP94 P49795	Q86WC4
PDB IDs		1CMZ	7BXU 7JM7
Enriched GO Terms of Interacting Partners?
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