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SIGMAR1 and RECK
Data Source:
BioGRID
(pull down)
SIGMAR1
RECK
Description
sigma non-opioid intracellular receptor 1
reversion inducing cysteine rich protein with kazal motifs
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Inner Membrane
Nuclear Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Lipid Droplet
Postsynaptic Density
Membrane
Integral Component Of Membrane
Growth Cone
Cytoplasmic Vesicle
Postsynaptic Density Membrane
Extracellular Region
Plasma Membrane
Membrane
Anchored Component Of Membrane
Wnt Signalosome
Molecular Function
Opioid Receptor Activity
Protein Binding
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Metalloendopeptidase Inhibitor Activity
Wnt-protein Binding
Coreceptor Activity Involved In Canonical Wnt Signaling Pathway
Biological Process
Lipid Transport
Nervous System Development
Cell Death In Response To Hydrogen Peroxide
Opioid Receptor Signaling Pathway
Regulation Of Neuron Apoptotic Process
Protein Homotrimerization
Blood Vessel Maturation
Sprouting Angiogenesis
Embryo Implantation
Extracellular Matrix Organization
Negative Regulation Of Cell Migration
Embryonic Forelimb Morphogenesis
Regulation Of Angiogenesis
Canonical Wnt Signaling Pathway
Regulation Of Establishment Of Blood-brain Barrier
Positive Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Metalloendopeptidase Activity
Pathways
Potential therapeutics for SARS
Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Amitriptyline
Remoxipride
Haloperidol
Dextromethorphan
Nortriptyline
Fenfluramine
Pentazocine
Cocaine
Hydrocodone
Sertraline
Dimethyltryptamine
Prasterone
Phencyclidine
Noscapine
Captodiame
Pentoxyverine
Diseases
GWAS
Bipolar disorder (inflammation and infection response interaction) (
25781172
)
IgG glycosylation (
23382691
)
Interacting Genes
3 interacting genes:
ANK2
ITPR3
PDZD11
42 interacting genes:
ADAM12
BMF
C22orf39
CCN3
CEP44
CFP
CTH
CTIF
CYSRT1
DISC1
EFHC2
GLRX3
INCA1
KEAP1
KLHL20
KRT40
KRTAP10-8
KRTAP13-2
KRTAP26-1
KRTAP3-1
LCN1
MEOX2
MLPH
MMP9
MTNR1B
NBPF19
NDUFB7
NOTCH2NLA
NR4A3
NUDT16L1
OXER1
PRIM2
REL
SPSB2
SSC4D
TCF4
TEKT4
TRIM39
TRIM69
USHBP1
ZNF438
ZNF704
Entrez ID
10280
8434
HPRD ID
03580
05567
Ensembl ID
ENSG00000147955
ENSG00000122707
Uniprot IDs
A2A3U5
B4DR71
Q99720
A8K9D8
O95980
Q6P9E2
PDB IDs
5HK1
5HK2
6DJZ
6DK0
6DK1
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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