DNAL4 and UBA7

Data Source:
BioGRID (enzymatic study)

		DNAL4	UBA7
Description		dynein axonemal light chain 4	ubiquitin like modifier activating enzyme 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding ISG15 Activating Enzyme Activity
	Biological Process	Microtubule-based Movement Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed	Cellular Protein Modification Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein Phosphopantetheinylation Modification-dependent Protein Catabolic Process ISG15-protein Conjugation Protein Modification By Small Protein Conjugation Negative Regulation Of Type I Interferon Production
Pathways		Retrograde neurotrophin signalling	ISG15 antiviral mechanism DDX58/IFIH1-mediated induction of interferon-alpha/beta Termination of translesion DNA synthesis Negative regulators of DDX58/IFIH1 signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Menarche (age at onset) ( 25231870) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)
Interacting Genes		16 interacting genes: CAMK2D CHIC2 DYNLL1 DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 KRTAP12-3 KRTAP9-8 NFATC2IP NOTCH2NLA NTAQ1 NUDT22 SCTR TRIM54	5 interacting genes: FAS ISG15 UBE2E1 UBE2L3 UBE2L6
Entrez ID		10126	7318
HPRD ID		13239	01873
Ensembl ID		ENSG00000100246	ENSG00000182179
Uniprot IDs		O96015	P41226
PDB IDs
Enriched GO Terms of Interacting Partners?
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