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NBPF19 and ADAM12
Data Source:
BioGRID
(two hybrid)
NBPF19
ADAM12
Description
NBPF member 19
ADAM metallopeptidase domain 12
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Extracellular Region
Nucleoplasm
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Metalloendopeptidase Activity
Protein Binding
Metallopeptidase Activity
SH3 Domain Binding
Metal Ion Binding
Biological Process
Proteolysis
Cell Adhesion
Myoblast Fusion
Extracellular Matrix Organization
Positive Regulation Of Angiogenesis
Pathways
Signaling by EGFR
Invadopodia formation
Drugs
Diseases
GWAS
Serum uric acid levels (
30993211
)
Blood protein levels (
30072576
)
Endometrial cancer (
24096698
)
Extremely high intelligence (
29731509
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
30054594
)
Itch intensity from mosquito bite (
28199695
)
Loneliness (
27629369
)
Metabolite levels (5-HIAA/ MHPG Ratio) (
23319000
)
Mild influenza (H1N1) infection (
26379185
)
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder (
26184070
27021288
)
Placental abruption (
29884306
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Visceral fat (
22589738
)
Interacting Genes
223 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALDH16A1
ALPP
ANKS1A
AQP1
ATG9A
ATP5F1D
BCAM
BMP7
BRME1
CARHSP1
CATSPER1
CCER1
CD164
CELF5
CERK
CHCHD3
CHIC2
CHRD
CHRNG
CNNM3
COL8A1
CREB5
CRH
CRY2
CST2
CST9L
CTNNBIP1
CTSZ
CXCL16
CYHR1
CYP21A2
CYSRT1
DAGLB
DALRD3
DBH
DGKQ
DHRS1
DMRT3
DOCK2
DRD5
EMC7
F10
FADS2
FAM221A
FAM71C
FAM90A1
FBXW5
FRS3
FTHL17
FZD10
GLP1R
GLYAT
GNE
GSTP1
HAPLN2
HBA1
HBA2
HBZ
HCK
HHEX
HOXA1
HOXB9
HOXC8
HPCAL1
HSPA12B
ICAM4
IL10
INO80B
INS
ITGB2
ITGB4
ITGB5
JOSD1
KCNS2
KCTD15
KLHL38
KLK8
KPRP
KRT83
KRTAP10-1
KRTAP10-10
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP4-11
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LMNTD2
LNX1
LRFN4
LYVE1
MACO1
MAPKBP1
MELTF
MFSD13A
MOS
MRGBP
MRPL40
MTA1
MXD3
MXI1
MYO15B
MYPOP
NECTIN2
NECTIN3
NEDD9
NMU
NPDC1
NR1D2
NTM
NTN4
OLFM2
OTX1
P2RX4
P2RX7
P2RY6
PCSK5
PGAP6
PHLDA1
PIGS
PLEKHN1
PRF1
PRR35
PSMA1
PTK7
PTPMT1
PVR
R3HDM2
RAB3IL1
RAMP3
RASD1
RECK
RNF111
RPS19BP1
RTN4RL1
SCNM1
SEMA3B
SEMA4C
SHFL
SLC22A5
SLC23A1
SLC43A2
SLC5A5
SLC6A20
SMCP
SPATA24
SPATA8
SPG7
SPPL2C
SPRY1
STAC
STK16
TAPBPL
TCAF1
THAP7
TLE5
TMEFF2
TMEM150A
TMIE
TNIP3
TNS2
TRAPPC14
TRIM42
TROAP
TSPAN4
TTPA
UTP23
UXT
VASN
WDR25
ZDHHC1
ZNF124
ZNF319
ZNF330
ZNF408
ZNF414
ZNF417
ZNF440
ZNF446
ZNF497
ZNF580
ZNF581
ZNF587
ZNF648
ZNF672
ZNF786
ZNF837
40 interacting genes:
ACTN2
ADAMTSL4
CYSRT1
EGF
ESM1
FHL5
FSTL3
GRB2
GUCD1
HOXA1
IGFBP3
IGFBP5
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-8
KRTAP12-2
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP5-6
KRTAP5-9
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE5A
MAPKBP1
NBPF19
NOTCH2NLA
OTX1
PACSIN3
PIK3R1
RECK
SH3D19
SLC15A2
SPRY1
SPRY4
SRC
TFAP2D
YES1
Entrez ID
101060226
8038
HPRD ID
04092
Ensembl ID
ENSG00000271383
ENSG00000148848
Uniprot IDs
A8K6G4
O43184
U5NE98
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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