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NBPF19 and AQP1
Data Source:
BioGRID
(two hybrid)
NBPF19
AQP1
Description
NBPF member 19
aquaporin 1 (Colton blood group)
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Serum uric acid levels (
30993211
)
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
223 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALDH16A1
ALPP
ANKS1A
AQP1
ATG9A
ATP5F1D
BCAM
BMP7
BRME1
CARHSP1
CATSPER1
CCER1
CD164
CELF5
CERK
CHCHD3
CHIC2
CHRD
CHRNG
CNNM3
COL8A1
CREB5
CRH
CRY2
CST2
CST9L
CTNNBIP1
CTSZ
CXCL16
CYHR1
CYP21A2
CYSRT1
DAGLB
DALRD3
DBH
DGKQ
DHRS1
DMRT3
DOCK2
DRD5
EMC7
F10
FADS2
FAM221A
FAM71C
FAM90A1
FBXW5
FRS3
FTHL17
FZD10
GLP1R
GLYAT
GNE
GSTP1
HAPLN2
HBA1
HBA2
HBZ
HCK
HHEX
HOXA1
HOXB9
HOXC8
HPCAL1
HSPA12B
ICAM4
IL10
INO80B
INS
ITGB2
ITGB4
ITGB5
JOSD1
KCNS2
KCTD15
KLHL38
KLK8
KPRP
KRT83
KRTAP10-1
KRTAP10-10
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP4-11
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LMNTD2
LNX1
LRFN4
LYVE1
MACO1
MAPKBP1
MELTF
MFSD13A
MOS
MRGBP
MRPL40
MTA1
MXD3
MXI1
MYO15B
MYPOP
NECTIN2
NECTIN3
NEDD9
NMU
NPDC1
NR1D2
NTM
NTN4
OLFM2
OTX1
P2RX4
P2RX7
P2RY6
PCSK5
PGAP6
PHLDA1
PIGS
PLEKHN1
PRF1
PRR35
PSMA1
PTK7
PTPMT1
PVR
R3HDM2
RAB3IL1
RAMP3
RASD1
RECK
RNF111
RPS19BP1
RTN4RL1
SCNM1
SEMA3B
SEMA4C
SHFL
SLC22A5
SLC23A1
SLC43A2
SLC5A5
SLC6A20
SMCP
SPATA24
SPATA8
SPG7
SPPL2C
SPRY1
STAC
STK16
TAPBPL
TCAF1
THAP7
TLE5
TMEFF2
TMEM150A
TMIE
TNIP3
TNS2
TRAPPC14
TRIM42
TROAP
TSPAN4
TTPA
UTP23
UXT
VASN
WDR25
ZDHHC1
ZNF124
ZNF319
ZNF330
ZNF408
ZNF414
ZNF417
ZNF440
ZNF446
ZNF497
ZNF580
ZNF581
ZNF587
ZNF648
ZNF672
ZNF786
ZNF837
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
Entrez ID
101060226
358
HPRD ID
00140
Ensembl ID
ENSG00000271383
ENSG00000240583
Uniprot IDs
A0A024RA31
P29972
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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