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AIFM1

Description apoptosis inducing factor mitochondria associated 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Intermembrane Space
  • Cytosol
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • DNA Binding
  • Protein Binding
  • NAD(P)H Oxidase H2O2-forming Activity
  • Oxidoreductase Activity, Acting On NAD(P)H
  • Protein Dimerization Activity
  • FAD Binding
Biological Process
  • Apoptotic Process
  • Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Chromosome Condensation
  • Mitochondrial Respiratory Chain Complex Assembly
  • Positive Regulation Of Apoptotic Process
  • Protein Import Into Mitochondrial Intermembrane Space
  • Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
Drugs
  • Flavin adenine dinucleotide
  • MCC
Diseases
  • Combined oxidative phosphorylation deficiency (COXPD)
GWAS
  • Bipolar disorder ( 31043756)
Novel Interacting Genes 1 novel interacting genes: DCAF7
Interacting Genes 11 interacting genes: CASP3 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP
Entrez ID 9131
HPRD ID 02161
Ensembl ID ENSG00000156709
Uniprot IDs E9PMA0 O95831
PDB IDs 1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025