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WNT3A
Description
Wnt family member 3A
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Cell Surface
Endocytic Vesicle Membrane
Early Endosome Membrane
Extracellular Exosome
Presynapse
Glutamatergic Synapse
Wnt-Frizzled-LRP5/6 Complex
Molecular Function
Transcription Coactivator Activity
Signaling Receptor Binding
Frizzled Binding
Cytokine Activity
Protein Binding
Protein Domain Specific Binding
Co-receptor Binding
Receptor Ligand Activity
Biological Process
Osteoblast Differentiation
In Utero Embryonic Development
Positive Regulation Of Cytokine Production
Positive Regulation Of Protein Phosphorylation
Heart Looping
Positive Regulation Of Receptor Internalization
Negative Regulation Of Heart Induction By Canonical Wnt Signaling Pathway
Axon Guidance
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
COP9 Signalosome Assembly
Positive Regulation Of Gene Expression
Negative Regulation Of Neuron Projection Development
Wnt Signaling Pathway
Spinal Cord Association Neuron Differentiation
Hippocampus Development
Cell Proliferation In Forebrain
Wnt Signaling Pathway Involved In Forebrain Neuroblast Division
Dorsal/ventral Neural Tube Patterning
Hemopoiesis
Neuron Differentiation
Extracellular Matrix Organization
Mammary Gland Development
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Protein Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Cell Proliferation In Midbrain
Cellular Protein Localization
Skeletal Muscle Cell Differentiation
Post-anal Tail Morphogenesis
Synaptic Vesicle Recycling
Inner Ear Morphogenesis
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Fate Commitment
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Somatic Stem Cell Division
Positive Regulation Of Mesodermal Cell Fate Specification
Paraxial Mesodermal Cell Fate Commitment
Positive Regulation Of Skeletal Muscle Tissue Development
Positive Regulation Of Collateral Sprouting In Absence Of Injury
Negative Regulation Of Axon Extension Involved In Axon Guidance
Negative Regulation Of Neurogenesis
Modulation Of Chemical Synaptic Transmission
Regulation Of Synapse Organization
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Positive Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Dermatome Development
Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Secondary Palate Development
Regulation Of Microtubule Cytoskeleton Organization
Platelet Aggregation
Cellular Response To Retinoic Acid
Axis Elongation Involved In Somitogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Calcium Ion Transmembrane Transport Via Low Voltage-gated Calcium Channel
Presynapse Assembly
Postsynapse To Nucleus Signaling Pathway
Negative Regulation Of Neuron Death
Positive Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of Dopaminergic Neuron Differentiation
Positive Regulation Of Core Promoter Binding
Beta-catenin Destruction Complex Disassembly
Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation
Regulation Of Presynapse Assembly
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Controlling Type B Pancreatic Cell Proliferation
Positive Regulation Of Neural Precursor Cell Proliferation
Positive Regulation Of Hepatocyte Proliferation
Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways
TCF dependent signaling in response to WNT
TCF dependent signaling in response to WNT
WNT ligand biogenesis and trafficking
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Regulation of FZD by ubiquitination
Signaling by RNF43 mutants
Drugs
Diseases
GWAS
Birth weight (
31043758
)
Diastolic blood pressure (
28135244
)
Height (
31562340
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Interacting Genes
11 interacting genes:
DLG1
DLG2
DLG4
FZD1
GPC3
LRP1
LRP6
PORCN
RYK
WNT1
WNT2
Entrez ID
89780
HPRD ID
05897
Ensembl ID
ENSG00000154342
Uniprot IDs
P56704
PDB IDs
Enriched GO Terms of Interacting Partners
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