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TNFRSF18

Description TNF receptor superfamily member 18
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
Molecular Function
  • Tumor Necrosis Factor-activated Receptor Activity
  • Protein Binding
Biological Process
  • Positive Regulation Of Leukocyte Migration
  • Apoptotic Process
  • Signal Transduction
  • Tumor Necrosis Factor-mediated Signaling Pathway
  • Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
  • Negative Regulation Of Apoptotic Process
  • Regulation Of Regulatory T Cell Differentiation
  • Positive Regulation Of Cell Adhesion
Pathways
  • TNFs bind their physiological receptors
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Novel Interacting Genes 7 novel interacting genes: AKR1C1 ARHGEF16 BTK DZIP3 KCNAB2 LGALS8 WRAP73
Interacting Genes 6 interacting genes: LNX1 TNFSF18 TRAF1 TRAF2 TRAF3 UBQLN2
Entrez ID 8784
HPRD ID 04879
Ensembl ID ENSG00000186891
Uniprot IDs A0A0R7FDM1 Q9Y5U5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025