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TPST1

Description tyrosylprotein sulfotransferase 1
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Golgi Apparatus
  • Membrane
  • Integral Component Of Golgi Membrane
Molecular Function
  • Sulfotransferase Activity
  • Protein-tyrosine Sulfotransferase Activity
  • Protein Homodimerization Activity
Biological Process
  • Peptidyl-tyrosine Sulfation
  • Inflammatory Response
  • Protein Phosphopantetheinylation
  • 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways
  • Cytosolic sulfonation of small molecules
  • Gamma carboxylation, hypusine formation and arylsulfatase activation
  • Defective F8 sulfation at Y1699
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Gout ( 22179738)
Interacting Genes 6 interacting genes: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG
Entrez ID 8460
HPRD ID 07216
Ensembl ID ENSG00000169902
Uniprot IDs A0A024RDK9 O60507
PDB IDs 5WRI 5WRJ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025