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SHOC2

Description SHOC2 leucine rich repeat scaffold protein
Image No pdb structure
GO Annotations Cellular Component
  • Protein Phosphatase Type 1 Complex
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
Molecular Function
  • Protein Binding
  • Protein Phosphatase 1 Binding
  • Protein Phosphatase Regulator Activity
  • Protein Phosphatase Binding
Biological Process
  • Signal Transduction
  • Ras Protein Signal Transduction
  • Fibroblast Growth Factor Receptor Signaling Pathway
  • Regulation Of Phosphoprotein Phosphatase Activity
  • Positive Regulation Of Ras Protein Signal Transduction
Pathways
  • RAF activation
  • Signaling by MRAS-complex mutants
Drugs
Diseases
  • Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
GWAS
  • Fish- and plant-related diet ( 32066663)
Interacting Genes 8 interacting genes: APP ERBIN HRAS KRAS NRAS PSMC5 RAF1 UBE2D3
Entrez ID 8036
HPRD ID 04144
Ensembl ID ENSG00000108061
Uniprot IDs Q9UQ13
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025