E2F8

Description		E2F transcription factor 8
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Placenta Development Sprouting Angiogenesis Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Cell Population Proliferation Negative Regulation Of Cytokinesis Positive Regulation Of DNA Endoreduplication Cell Cycle Comprising Mitosis Without Cytokinesis Positive Regulation Of Transcription By RNA Polymerase II Trophoblast Giant Cell Differentiation Chorionic Trophoblast Cell Differentiation Hepatocyte Differentiation
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)
Interacting Genes		8 interacting genes: APP EWSR1 FHL3 LZTR1 MEOX2 STUB1 TFCP2 ZDHHC17
Entrez ID		79733
HPRD ID		10981
Ensembl ID		ENSG00000129173
Uniprot IDs		A0AVK6
PDB IDs		4YO2
Enriched GO Terms of Interacting Partners?
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