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ZIC2

Description Zic family member 2
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Nuclear Body
Molecular Function
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA Binding
  • DNA-binding Transcription Factor Activity
  • Chromatin DNA Binding
  • Metal Ion Binding
Biological Process
  • Regulation Of Transcription By RNA Polymerase II
  • Central Nervous System Development
  • Brain Development
  • Visual Perception
  • Cell Differentiation
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription, DNA-templated
  • Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways
Drugs
Diseases
  • Holoprosencephaly (HPE)
GWAS
  • Hyperopia ( 25233373)
  • Myopia ( 27182965)
  • Refractive error ( 23396134 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 3 interacting genes: GLI1 GLI2 GLI3
Entrez ID 7546
HPRD ID 04353
Ensembl ID ENSG00000043355
Uniprot IDs A0A024RDY6 O95409
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025