WNT2B

Description		Wnt family member 2B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix
	Molecular Function	Frizzled Binding Cytokine Activity
	Biological Process	Chondrocyte Differentiation Lens Development In Camera-type Eye Male Gonad Development Cellular Response To Starvation Wnt Signaling Pathway Forebrain Regionalization Neuron Differentiation Cell Fate Commitment Canonical Wnt Signaling Pathway Lung Induction Mesenchymal-epithelial Cell Signaling Iris Morphogenesis Cornea Development In Camera-type Eye Hematopoietic Stem Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Pathways		WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 29403010 30487518) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Heel bone mineral density ( 30598549 28869591) Hypertension ( 30487518) Ischemic stroke ( 29531354) Mean arterial pressure ( 29403010 30487518) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Pancreatic cancer ( 29422604 26098869) Potassium levels ( 29403010) Pulse pressure ( 30487518) Stroke ( 29531354) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 29403010 30487518 30578418) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		2 interacting genes: BRCA1 RAD21
Entrez ID		7482
HPRD ID		03574
Ensembl ID		ENSG00000134245
Uniprot IDs		Q5TEH8 Q93097
PDB IDs
Enriched GO Terms of Interacting Partners?
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