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TTPA

Description alpha tocopherol transfer protein
Image
GO Annotations Cellular Component
  • Late Endosome
  • Cytosol
Molecular Function
  • Protein Binding
  • Phosphatidylinositol-4,5-bisphosphate Binding
  • Vitamin E Binding
  • Phosphatidylinositol-3,4-bisphosphate Binding
  • Lipid Transfer Activity
  • Phosphatidylinositol Bisphosphate Binding
Biological Process
  • Lipid Metabolic Process
  • Response To Nutrient
  • Response To PH
  • Developmental Process
  • Vitamin E Metabolic Process
  • Vitamin Transport
  • Intracellular PH Reduction
  • Negative Regulation Of Cell Death
  • Intermembrane Lipid Transfer
Pathways
  • Vitamin E
Drugs
Diseases
  • Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS
Novel Interacting Genes 1 novel interacting genes: MMS22L
Interacting Genes 46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52
Entrez ID 7274
HPRD ID 02685
Ensembl ID ENSG00000137561
Uniprot IDs P49638
PDB IDs 1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025