C4B

Description		complement C4B (Chido blood group)
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Axon Dendrite Other Organism Cell Synapse Extracellular Exosome Blood Microparticle
	Molecular Function	Complement Binding Endopeptidase Inhibitor Activity Carbohydrate Binding
	Biological Process	Inflammatory Response Complement Activation Complement Activation, Classical Pathway Opsonization Negative Regulation Of Endopeptidase Activity Regulation Of Complement Activation Detection Of Molecule Of Bacterial Origin Innate Immune Response Positive Regulation Of Apoptotic Cell Clearance
Pathways		Initial triggering of complement Activation of C3 and C5 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Regulation of Complement cascade Initial triggering of complement Activation of C3 and C5 Regulation of Complement cascade
Drugs		Human immunoglobulin G Human immunoglobulin G Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Feeling worry ( 29500382) Inflammatory bowel disease ( 28067908) Neuromyelitis optica ( 29769526) Neuromyelitis optica (AQP4-IgG-positive) ( 29769526) Prostate cancer ( 23535732) Reticulocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: C2
Entrez ID		721
HPRD ID
Ensembl ID		ENSG00000224389
Uniprot IDs		P0C0L4 P0C0L5
PDB IDs		1HZF 4FXG 4FXK 4XAM 5JPM 5JPN 5JTW 6YSQ
Enriched GO Terms of Interacting Partners?
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