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SKI
Description
SKI proto-oncogene
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Centrosome
Nuclear Body
PML Body
Transcription Repressor Complex
Protein-containing Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
SMAD Binding
Histone Deacetylase Inhibitor Activity
Repressing Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neural Tube Closure
Lens Morphogenesis In Camera-type Eye
Transcription, DNA-templated
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Anterior/posterior Axis Specification
Negative Regulation Of Schwann Cell Proliferation
Myotube Differentiation
Olfactory Bulb Development
Myelination In Peripheral Nervous System
Positive Regulation Of Wnt Signaling Pathway
Embryonic Limb Morphogenesis
BMP Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Negative Regulation Of Histone Deacetylation
Negative Regulation Of Activin Receptor Signaling Pathway
Somatic Stem Cell Population Maintenance
Camera-type Eye Development
Positive Regulation Of DNA Binding
Nose Morphogenesis
Negative Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Skeletal Muscle Fiber Development
Cell Motility
Roof Of Mouth Development
Retina Development In Camera-type Eye
Face Morphogenesis
Bone Morphogenesis
SMAD Protein Signal Transduction
Pathways
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Coronary artery disease (
29212778
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
Plateletcrit (
32888494
)
PR interval (
30046033
32439900
)
Systolic blood pressure (
30224653
)
Urate levels (
31578528
)
Interacting Genes
20 interacting genes:
AKT1
GLI2
GLI3
HIPK2
JUN
MECP2
MYB
NCOR1
NFIX
PML
SIN3A
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SNW1
SPI1
TGFBR1
TRIM28
Entrez ID
6497
HPRD ID
01271
Ensembl ID
ENSG00000157933
Uniprot IDs
P12755
PDB IDs
1MR1
1SBX
5XOD
Enriched GO Terms of Interacting Partners
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