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EDA2R

Description ectodysplasin A2 receptor
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Tumor Necrosis Factor-activated Receptor Activity
  • Protein Binding
  • Signaling Receptor Activity
Biological Process
  • Multicellular Organism Development
  • Epidermis Development
  • Ectodermal Cell Differentiation
  • Tumor Necrosis Factor-mediated Signaling Pathway
  • Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
  • Positive Regulation Of JNK Cascade
  • Positive Regulation Of NF-kappaB Transcription Factor Activity
  • Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
  • TNFs bind their physiological receptors
Drugs
Diseases
GWAS
  • Balding ( 26926045)
  • Male-pattern baldness ( 27182965 22032556 28196072)
Novel Interacting Genes 1 novel interacting genes: SUFU
Interacting Genes 16 interacting genes: AGR3 ATP6V0C C1QB CASP8 CEBPE EDA FADD GIMAP5 JAGN1 NKG7 PLP1 SGTA STRIT1 TMEM262 TRAF3 TRAF6
Entrez ID 60401
HPRD ID 02230
Ensembl ID ENSG00000131080
Uniprot IDs B2RBZ9 B4DQY6 Q9HAV5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025