REV3L

Description		REV3 like, DNA directed polymerase zeta catalytic subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Zeta DNA Polymerase Complex
	Molecular Function	Nucleotide Binding DNA Binding DNA-directed DNA Polymerase Activity Protein Binding 3'-5' Exonuclease Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA-dependent DNA Replication Error-prone Translesion Synthesis Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 26414677) Psoriasis ( 25574825) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549) Ulcerative colitis ( 28067908)
Novel Interacting Genes		1 novel interacting genes: HDAC2
Interacting Genes		5 interacting genes: CHEK2 HDAC4 MAD2L1 MAD2L2 REV1
Entrez ID		5980
HPRD ID		04145
Ensembl ID		ENSG00000009413
Uniprot IDs		O60673 Q9UG47
PDB IDs		3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5O8K 6BC8 6BCD 6BI7 6EKM 6KEA
Enriched GO Terms of Interacting Partners?
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