Wiki-Pi
About
Search
Browse
People
Updates
Search
REN
Description
renin
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Apical Part Of Cell
Molecular Function
Aspartic-type Endopeptidase Activity
Signaling Receptor Binding
Insulin-like Growth Factor Receptor Binding
Protein Binding
Peptidase Activity
Biological Process
Kidney Development
Mesonephros Development
Angiotensin Maturation
Renin-angiotensin Regulation Of Aldosterone Production
Proteolysis
Regulation Of Blood Pressure
Male Gonad Development
Hormone-mediated Signaling Pathway
Response To Lipopolysaccharide
Cellular Response To Drug
Response To Immobilization Stress
Drinking Behavior
Regulation Of MAPK Cascade
Cell Maturation
Amyloid-beta Metabolic Process
Response To CAMP
Response To CGMP
Pathways
Metabolism of Angiotensinogen to Angiotensins
Drugs
Remikiren
Minoxidil
Lisinopril
N,N-dimethylformamide
Isoamyl alcohol
3-Phenyl-1,2-Propandiol
2-Methyl-3-(2-Aminothiazolo)Propanal
Enalkiren
2-Cyclopropylmethylenepropanal
1-Methyl-2-Oxy-5,5-Dimethyl Pyrrolidine
N-Methyl-N-(Methylbenzyl)Formamide
1-Hydroxy-2-Amino-3-Cyclohexylpropane
SPP1148
ZOTHIAZIN-4-YL]ETHYL}ACETAMIDE
6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE
N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL]ETHYL}ACETAMIDE
(2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE
6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE
5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE
6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine
Aliskiren
Diseases
Renal tubular dysgenesis
Uromodulin-associated kidney diseases, including: Medullary cystic kidney disease 2; Familial juvenile hyperuremic nephropathy; Glomerulocystic kidney disease
GWAS
Blood protein levels (
29875488
)
Blood protein levels in cardiovascular risk (
28369058
)
Response to cognitive-behavioural therapy in anxiety disorder (
31123309
)
Interacting Genes
9 interacting genes:
AGT
ATP6AP2
CCDC24
CTSB
KCTD15
M6PR
PCSK1
PCSK5
RENBP
Entrez ID
5972
HPRD ID
01564
Ensembl ID
ENSG00000143839
Uniprot IDs
P00797
PDB IDs
1BBS
1BIL
1BIM
1HRN
1RNE
2BKS
2BKT
2FS4
2G1N
2G1O
2G1R
2G1S
2G1Y
2G20
2G21
2G22
2G24
2G26
2G27
2I4Q
2IKO
2IKU
2IL2
2REN
2V0Z
2V10
2V11
2V12
2V13
2V16
2X0B
3D91
3G6Z
3G70
3G72
3GW5
3K1W
3KM4
3O9L
3OAD
3OAG
3OOT
3OQF
3OQK
3OWN
3Q3T
3Q4B
3Q5H
3SFC
3VCM
3VSW
3VSX
3VUC
3VYD
3VYE
3VYF
4AMT
4GJ5
4GJ6
4GJ7
4GJ8
4GJ9
4GJA
4GJB
4GJC
4GJD
4PYV
4Q1N
4RYC
4RYG
4RZ1
4S1G
4XX3
4XX4
5KOQ
5KOS
5KOT
5SXN
5SY2
5SY3
5SZ9
5T4S
5TMG
5TMK
5V8V
5VPM
5VRP
6I3F
Enriched GO Terms of Interacting Partners
?
Tagcloud
?