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RASGRF1
Description
Ras protein specific guanine nucleotide releasing factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Growth Cone
Neuron Projection
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Glutamate Receptor Binding
Biological Process
MAPK Cascade
Signal Transduction
Small GTPase Mediated Signal Transduction
Long-term Memory
Cell Population Proliferation
Neuron Projection Development
Response To Endoplasmic Reticulum Stress
Regulation Of Rac Protein Signal Transduction
Regulation Of Rho Protein Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Ras Protein Signal Transduction
Regulation Of Synaptic Plasticity
Regulation Of Neuronal Synaptic Plasticity
Activation Of GTPase Activity
Regulation Of NMDA Receptor Activity
Pathways
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Bronchopulmonary dysplasia (
23897914
)
Hand grip strength (
29691431
)
High myopia (
32428537
)
Myopia (
27182965
)
Refractive error (
23396134
32231278
20835236
)
RR interval (heart rate) (
20031603
)
Spherical equivalent (joint analysis main effects and education interaction) (
27020472
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
19 interacting genes:
CEBPA
EHD4
GRIN2B
GRK2
HRAS
NTRK1
NTRK2
NTRK3
PRKACA
RAC1
RHOA
RRAS2
SNRNP70
SRC
SRPK2
TNK2
USP8
YWHAB
YWHAE
Entrez ID
5923
HPRD ID
07362
Ensembl ID
ENSG00000058335
Uniprot IDs
A8K270
Q13972
Q8IUU5
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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