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SLC35C1

Description solute carrier family 35 member C1
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Golgi Apparatus
  • Integral Component Of Membrane
Molecular Function
  • GDP-fucose Transmembrane Transporter Activity
  • Antiporter Activity
Biological Process
  • Carbohydrate Transport
  • Lipid Glycosylation
  • Protein O-linked Fucosylation
  • GDP-fucose Import Into Golgi Lumen
  • Negative Regulation Of Notch Signaling Pathway
Pathways
  • Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)
  • GDP-fucose biosynthesis
  • Transport of nucleotide sugars
Drugs
Diseases
  • Congenital disorders of glycosylation (CDG) type II
  • Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
GWAS
  • Axial length ( 24144296)
  • Diastolic blood pressure ( 26969751)
  • Visceral fat ( 22589738)
Novel Interacting Genes 1 novel interacting genes: AMBRA1
Interacting Genes
Entrez ID 55343
HPRD ID 09324
Ensembl ID ENSG00000181830
Uniprot IDs B3KQH0 Q96A29
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025