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PDP1

Description pyruvate dehydrogenase phosphatase catalytic subunit 1
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Protein Serine/threonine Phosphatase Activity
  • Magnesium-dependent Protein Serine/threonine Phosphatase Activity
  • [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Protein Dephosphorylation
  • Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
  • Peptidyl-threonine Dephosphorylation
  • Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways
  • Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases
  • Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS
Novel Interacting Genes 1 novel interacting genes: PLEKHF2
Interacting Genes 10 interacting genes: ACAT1 CBFA2T2 EGFR FGFR1 INCA1 KRTAP6-2 MEOX2 PDHA1 PRKCD SIRT3
Entrez ID 54704
HPRD ID 16185
Ensembl ID ENSG00000164951
Uniprot IDs A0A024R9C0 Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025