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POU4F1
Description
POU class 4 homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Neuron Projection
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Single-stranded DNA Binding
Protein Binding
Sequence-specific DNA Binding
GTPase Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Suckling Behavior
Ventricular Compact Myocardium Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Axonogenesis
Synapse Assembly
Mesoderm Development
Heart Development
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Cell Migration In Hindbrain
Trigeminal Nerve Development
Central Nervous System Neuron Differentiation
Habenula Development
Neuron Projection Development
Positive Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Neuron Fate Specification
Sensory System Development
Peripheral Nervous System Neuron Development
Regulation Of Neurogenesis
Regulation Of DNA-binding Transcription Factor Activity
Proprioception Involved In Equilibrioception
Innervation
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Cytokine Stimulus
Cellular Response To Estradiol Stimulus
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Transcription Elongation By RNA Polymerase I
Pathways
Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS
Antipsychotic drug-induced weight gain in schizophrenia (
31447353
)
Total ventricular volume (Alzheimer's disease interaction) (
21116278
)
Novel Interacting Genes
1 novel interacting genes:
NDFIP2
Interacting Genes
4 interacting genes:
ESR1
EWSR1
MAPRE3
RIT2
Entrez ID
5457
HPRD ID
03379
Ensembl ID
ENSG00000152192
Uniprot IDs
Q01851
PDB IDs
Enriched GO Terms of Interacting Partners
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