CFP

Description		complement factor properdin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Tertiary Granule Lumen
	Molecular Function	Protein Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Regulation Of Complement Activation Defense Response To Bacterium Neutrophil Degranulation
Pathways		Alternative complement activation Activation of C3 and C5 Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins Neutrophil degranulation Regulation of Complement cascade
Drugs
Diseases		Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS
Novel Interacting Genes		1 novel interacting genes: ETS1
Interacting Genes		32 interacting genes: BANF2 C3 CFAP206 CFB CYSRT1 FHL5 FKBP6 GEMIN4 GNE HEXIM2 HOXA1 KCTD9 KLHL38 KRTAP11-1 KRTAP12-2 KRTAP3-1 KRTAP6-2 LCE1A LONRF1 MID2 MTOR NEK6 NOXA1 PRKAB2 RECK SMARCC1 SPAG8 STK16 TRIP13 VENTX ZNF330 ZNF414
Entrez ID		5199
HPRD ID		02308
Ensembl ID		ENSG00000126759
Uniprot IDs		A0A0S2Z4I5 P27918
PDB IDs		1W0R 1W0S 6RUR 6RUS 6RUV 6RV6 6S08 6S0A 6S0B 6SEJ
Enriched GO Terms of Interacting Partners?
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